Markers of glutamate synaptic transmission and plasticity are increased in the anterior cingulate cortex in bipolar disorder.
BACKGROUND: Cortical glutamate levels are elevated in bipolar disorder, but the interpretation of this increase is unclear because glutamate has metabolic as well as neurotransmitter roles. We investigated this by measuring vesicular glutamate transporter 1 (VGluT1) expression, which reflects activ...
Main Authors: | Eastwood, S, Harrison, P |
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Format: | Journal article |
Language: | English |
Published: |
2010
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