Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar.

Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar.

In mammalian systems, the heterodimeric basic helix-loop-helix (bHLH)-PAS transcription hypoxia-inducible factor (HIF) has emerged as the key regulator of responses to hypoxia. Here we define a homologous system in Drosophila melanogaster, and we characterize its activity in vivo during development....

書目詳細資料
Main Authors:	Lavista-Llanos, S, Centanin, L, Irisarri, M, Russo, D, Gleadle, J, Bocca, SN, Muzzopappa, M, Ratcliffe, P, Wappner, P
格式:	Journal article
語言:	English
出版:	2002

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