Control of the hypoxic response in Drosophila melanogaster by the basic helix-loop-helix PAS protein similar.

In mammalian systems, the heterodimeric basic helix-loop-helix (bHLH)-PAS transcription hypoxia-inducible factor (HIF) has emerged as the key regulator of responses to hypoxia. Here we define a homologous system in Drosophila melanogaster, and we characterize its activity in vivo during development....

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Lavista-Llanos, S, Centanin, L, Irisarri, M, Russo, D, Gleadle, J, Bocca, SN, Muzzopappa, M, Ratcliffe, P, Wappner, P
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2002