Expression of four alternative dystrophin transcripts in brain regions regulated by different promoters.
Cognitive impairment occurs in one-third of patients with Duchenne muscular dystrophy, a lethal X-linked, recessive disease caused by mutations in the dystrophin gene which is expressed in both brain and muscle, the two transcripts having alternative first exons. Previous reports have indicated that...
Asıl Yazarlar: | Górecki, D, Monaco, A, Derry, J, Walker, A, Barnard, E, Barnard, P |
---|---|
Materyal Türü: | Journal article |
Dil: | English |
Baskı/Yayın Bilgisi: |
1992
|
Benzer Materyaller
-
Alternative splicing of dystrobrevin regulates the stoichiometry of syntrophin binding to the dystrophin protein complex.
Yazar:: Newey, S, ve diğerleri
Baskı/Yayın Bilgisi: (2000) -
DIVERSITY OF THE DYSTROPHIN GENE-PRODUCTS
Yazar:: Chelly, J, ve diğerleri
Baskı/Yayın Bilgisi: (1993) -
Distal transcript of the dystrophin gene initiated from an alternative first exon and encoding a 75-kDa protein widely distributed in nonmuscle tissues.
Yazar:: Hugnot, J, ve diğerleri
Baskı/Yayın Bilgisi: (1992) -
Function and genetics of dystrophin and dystrophin-related proteins in muscle.
Yazar:: Blake, D, ve diğerleri
Baskı/Yayın Bilgisi: (2002) -
The Duchenne and Becker muscular dystrophy gene and protein product dystrophin
Yazar:: Monaco, A
Baskı/Yayın Bilgisi: (1989)