HTLV-1 associated myelopathy in Canada.

HTLV-1 associated myelopathy in Canada.

We report the clinical and laboratory findings of six Canadian patients with progressive myelopathy associated with HTLV-1 infection. The diagnosis was suspected on clinical grounds and supported by serological studies and positive gene amplification. Only five had emigrated from an area endemic for...

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Մատենագիտական մանրամասներ
Հիմնական հեղինակներ: Power, C, Weinshenker, BG, Dekaban, G, Ebers, G, Francis, G, Rice, G
Ձևաչափ: Journal article
Լեզու:English
Հրապարակվել է: 1989
Նկարագրություն
Ամփոփում:We report the clinical and laboratory findings of six Canadian patients with progressive myelopathy associated with HTLV-1 infection. The diagnosis was suspected on clinical grounds and supported by serological studies and positive gene amplification. Only five had emigrated from an area endemic for HTLV-1 infection. Tropical spastic paraparesis should be considered in all patients with myelopathy, even those without standard serological markers of HTLV-1 infection. The pathogenesis of this condition and the serological and molecular biological means by which this diagnosis can be made are reviewed.

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