HTLV-1 associated myelopathy in Canada.
We report the clinical and laboratory findings of six Canadian patients with progressive myelopathy associated with HTLV-1 infection. The diagnosis was suspected on clinical grounds and supported by serological studies and positive gene amplification. Only five had emigrated from an area endemic for...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1989
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| _version_ | 1826289807377039360 |
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| author | Power, C Weinshenker, BG Dekaban, G Ebers, G Francis, G Rice, G |
| author_facet | Power, C Weinshenker, BG Dekaban, G Ebers, G Francis, G Rice, G |
| author_sort | Power, C |
| collection | OXFORD |
| description | We report the clinical and laboratory findings of six Canadian patients with progressive myelopathy associated with HTLV-1 infection. The diagnosis was suspected on clinical grounds and supported by serological studies and positive gene amplification. Only five had emigrated from an area endemic for HTLV-1 infection. Tropical spastic paraparesis should be considered in all patients with myelopathy, even those without standard serological markers of HTLV-1 infection. The pathogenesis of this condition and the serological and molecular biological means by which this diagnosis can be made are reviewed. |
| first_indexed | 2024-03-07T02:34:32Z |
| format | Journal article |
| id | oxford-uuid:a858d74b-0306-43f5-9ee6-cec9170649b1 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:34:32Z |
| publishDate | 1989 |
| record_format | dspace |
| spelling | oxford-uuid:a858d74b-0306-43f5-9ee6-cec9170649b12022-03-27T03:00:53ZHTLV-1 associated myelopathy in Canada.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a858d74b-0306-43f5-9ee6-cec9170649b1EnglishSymplectic Elements at Oxford1989Power, CWeinshenker, BGDekaban, GEbers, GFrancis, GRice, GWe report the clinical and laboratory findings of six Canadian patients with progressive myelopathy associated with HTLV-1 infection. The diagnosis was suspected on clinical grounds and supported by serological studies and positive gene amplification. Only five had emigrated from an area endemic for HTLV-1 infection. Tropical spastic paraparesis should be considered in all patients with myelopathy, even those without standard serological markers of HTLV-1 infection. The pathogenesis of this condition and the serological and molecular biological means by which this diagnosis can be made are reviewed. |
| spellingShingle | Power, C Weinshenker, BG Dekaban, G Ebers, G Francis, G Rice, G HTLV-1 associated myelopathy in Canada. |
| title | HTLV-1 associated myelopathy in Canada. |
| title_full | HTLV-1 associated myelopathy in Canada. |
| title_fullStr | HTLV-1 associated myelopathy in Canada. |
| title_full_unstemmed | HTLV-1 associated myelopathy in Canada. |
| title_short | HTLV-1 associated myelopathy in Canada. |
| title_sort | htlv 1 associated myelopathy in canada |
| work_keys_str_mv | AT powerc htlv1associatedmyelopathyincanada AT weinshenkerbg htlv1associatedmyelopathyincanada AT dekabang htlv1associatedmyelopathyincanada AT ebersg htlv1associatedmyelopathyincanada AT francisg htlv1associatedmyelopathyincanada AT riceg htlv1associatedmyelopathyincanada |