Coherence analysis in the myoclonus of corticobasal degeneration.
We investigated whether myoclonus in corticobasal degeneration (CBD) is cortical or subcortical in origin. Many authors have suggested that the myoclonus in CBD is a subtype of cortical myoclonus, despite the fact that back-averaging fails to detect a cortical correlate to spontaneous or action indu...
| Príomhchruthaitheoirí: | , , , |
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| Formáid: | Journal article |
| Teanga: | English |
| Foilsithe / Cruthaithe: |
2003
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| _version_ | 1826289809734238208 |
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| author | Grosse, P Kühn, A Cordivari, C Brown, P |
| author_facet | Grosse, P Kühn, A Cordivari, C Brown, P |
| author_sort | Grosse, P |
| collection | OXFORD |
| description | We investigated whether myoclonus in corticobasal degeneration (CBD) is cortical or subcortical in origin. Many authors have suggested that the myoclonus in CBD is a subtype of cortical myoclonus, despite the fact that back-averaging fails to detect a cortical correlate to spontaneous or action induced jerks and giant sensory evoked potentials are seldom found. Electroencephalographic-electromyographic (EEG-EMG) and EMG-EMG frequency analysis may be more sensitive to cortical drives when EMG bursts occur at a high frequency and at low amplitudes as in CBD. We evaluated EEG-EMG and EMG-EMG coherence and phase in 5 patients with clinically probable CBD and unilateral, action-induced and stimulus-sensitive myoclonus. We found negligible corticomuscular coherence despite a dramatically exaggerated EMG-EMG coherence. We conclude that an inflated EMG-EMG coherence is found in some patients with CBD and that this is unlikely to be due to an exaggerated cortical drive. |
| first_indexed | 2024-03-07T02:34:34Z |
| format | Journal article |
| id | oxford-uuid:a85b5093-e57d-4194-916a-93564f8c92ed |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:34:34Z |
| publishDate | 2003 |
| record_format | dspace |
| spelling | oxford-uuid:a85b5093-e57d-4194-916a-93564f8c92ed2022-03-27T03:00:58ZCoherence analysis in the myoclonus of corticobasal degeneration.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a85b5093-e57d-4194-916a-93564f8c92edEnglishSymplectic Elements at Oxford2003Grosse, PKühn, ACordivari, CBrown, PWe investigated whether myoclonus in corticobasal degeneration (CBD) is cortical or subcortical in origin. Many authors have suggested that the myoclonus in CBD is a subtype of cortical myoclonus, despite the fact that back-averaging fails to detect a cortical correlate to spontaneous or action induced jerks and giant sensory evoked potentials are seldom found. Electroencephalographic-electromyographic (EEG-EMG) and EMG-EMG frequency analysis may be more sensitive to cortical drives when EMG bursts occur at a high frequency and at low amplitudes as in CBD. We evaluated EEG-EMG and EMG-EMG coherence and phase in 5 patients with clinically probable CBD and unilateral, action-induced and stimulus-sensitive myoclonus. We found negligible corticomuscular coherence despite a dramatically exaggerated EMG-EMG coherence. We conclude that an inflated EMG-EMG coherence is found in some patients with CBD and that this is unlikely to be due to an exaggerated cortical drive. |
| spellingShingle | Grosse, P Kühn, A Cordivari, C Brown, P Coherence analysis in the myoclonus of corticobasal degeneration. |
| title | Coherence analysis in the myoclonus of corticobasal degeneration. |
| title_full | Coherence analysis in the myoclonus of corticobasal degeneration. |
| title_fullStr | Coherence analysis in the myoclonus of corticobasal degeneration. |
| title_full_unstemmed | Coherence analysis in the myoclonus of corticobasal degeneration. |
| title_short | Coherence analysis in the myoclonus of corticobasal degeneration. |
| title_sort | coherence analysis in the myoclonus of corticobasal degeneration |
| work_keys_str_mv | AT grossep coherenceanalysisinthemyoclonusofcorticobasaldegeneration AT kuhna coherenceanalysisinthemyoclonusofcorticobasaldegeneration AT cordivaric coherenceanalysisinthemyoclonusofcorticobasaldegeneration AT brownp coherenceanalysisinthemyoclonusofcorticobasaldegeneration |