Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations.

Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations.

Osteoarthritis (OA) is the most common form of arthritis and a major cause of disability. This study evaluates the association in Caucasian populations of two single nucleotide polymorphisms (SNPs) mapping to the Human Leukocyte Antigen (HLA) region and deriving from a genome wide association scan (...

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Bibliographic Details
Main Authors: Valdes, A, Styrkarsdottir, U, Doherty, M, Morris, D, Mangino, M, Tamm, A, Doherty, SA, Kisand, K, Kerna, I, Wheeler, M, Maciewicz, R, Zhang, W, Muir, K, Dennison, E, Hart, D, Metrustry, S, Jonsdottir, I, Jonsson, G, Jonsson, H, Ingvarsson, T, Cooper, C, Vyse, T, Spector, T, Stefansson, K, Arden, N
Format: Journal article
Language:English
Published: Public Library of Science 2011

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