Determining targets for antiretroviral drug concentrations: a causal framework illustrated with pediatric efavirenz data from the CHAPAS-3 trial
<p><strong>Background: </strong>Determining a therapeutic window for maintaining antiretroviral drug concentrations within an appropriate range is required for identifying effective dosing regimens. The limits of this window are typically calculated using predictive models...
Główni autorzy: | Schomaker, M, Denti, P, Bienczak, A, Burger, D, Díaz, I, Gibb, DM, Walker, AS, McIlleron, H |
---|---|
Format: | Journal article |
Język: | English |
Wydane: |
Wiley
2024
|
Podobne zapisy
-
The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children
od: Bienczak, A, i wsp.
Wydane: (2016) -
Plasma efavirenz exposure, sex, and age predict virological response in HIV-infected African children.
od: Bienczak, A, i wsp.
Wydane: (2016) -
Evaluation of an immunoassay for determination of plasma efavirenz concentrations in resource‐limited settings
od: Alemseged Abdissa, i wsp.
Wydane: (2014-01-01) -
Pharmacokinetics of antiretroviral drugs in infancy
od: Helen McIlleron, i wsp.
Wydane: (2009-12-01) -
Determinants of virological outcome and adverse events in African children treated with paediatric nevirapine fixed-dose-combination tablets
od: Bienczak, A, i wsp.
Wydane: (2017)