Structural and regulatory diversity shape HLA-C protein expression levels

Structural and regulatory diversity shape HLA-C protein expression levels

Expression of HLA-C varies widely across individuals in an allele-specific manner. This variation in expression can influence efficacy of the immune response, as shown for infectious and autoimmune diseases. MicroRNA binding partially influences differential HLA-C expression, but the additional cont...

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Autors principals:	Kaur, G, Gras, S, Mobbs, J, Vivian, J, Cortes, A, Barber, T, Kuttikkatte, S, Jensen, L, Attfield, K, Dendrou, C, Carrington, M, McVean, G, Purcell, A, Rossjohn, J, Fugger, L
Format:	Journal article
Publicat:	Springer Nature 2017

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