T-cell activation through immunological synapses and kinapses.
T-cell activation requires 'contact' with antigen-presenting cells (APCs) to bring the T-cell receptor (TCR) and antigenic major histocompatibility complex (MHC)-peptide complex together. Contact is defined by the size of the TCR and MHC-peptide complex, which at approximately 13 nm requir...
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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