Role of the chaperone DnaK in protein solubility and conformational quality in inclusion body-forming Escherichia coli cells.
Misfolding-prone proteins produced in bacteria usually fail to adopt their native conformation and aggregate. In cells producing folding-reluctant protein species, folding modulators are supposed to be limiting, a fact that enhances protein deposition. Therefore, coproducing DnaK or other main chape...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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