Expression and immunolocalisation of neutral endopeptidase in prostate cancer.

BACKGROUND: Neutral Endopeptidase (NEP) is a cell surface enzyme that cleaves and inactivates neuropeptides. When present on androgen-dependent prostate cancer (PC) cells, NEP inactivates growth stimulatory neuropeptides. After androgen ablation NEP expression decreases and neuropeptides can enhanc...

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Autors principals: Albrecht, M, Mittler, A, Wilhelm, B, Lundwall, A, Lilja, H, Aumüller, G, Bjartell, A
Format: Journal article
Idioma:English
Publicat: 2003

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