THE MECHANISM OF ACTION OF PROTECTIN (CD59), A HOMOLOGOUS RESTRICTION FACTOR OF THE HUMAN-COMPLEMENT SYSTEM

Geahča maid

• Human protectin (CD59), an 18,000-20,000 MW complement lysis restricting factor, inhibits C5b-8 catalysed insertion of C9 into lipid bilayers.
  Dahkki: Meri, S, et al.
  Almmustuhtton: (1990)
• Distribution of protectin (CD59), a complement membrane attack inhibitor, in normal human tissues.
  Dahkki: Meri, S, et al.
  Almmustuhtton: (1991)
• CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells.
  Dahkki: Davies, A, et al.
  Almmustuhtton: (1989)
• Transfection of human CD59 complementary DNA into rat cells confers resistance to human complement.
  Dahkki: Walsh, L, et al.
  Almmustuhtton: (1991)
• The glycosylation of the complement regulatory protein, human erythrocyte CD59.
  Dahkki: Rudd, P, et al.
  Almmustuhtton: (1998)