Probing the structure of a potent acetylcholinesterase inhibitor in the binding site using solid state nuclear magnetic resonance.

Probing the structure of a potent acetylcholinesterase inhibitor in the binding site using solid state nuclear magnetic resonance.

Dettagli Bibliografici
Autori principali:	Goodall, S, Spooner, P, Middleton, D, Howe, P, Watts, A
Natura:	Journal article
Pubblicazione:	2002

Documenti analoghi

Probing the structure and dynamics of acetylcholinesterase inhibitors is the binding site using solid state NMR
di: Goodall, S, et al.
Pubblicazione: (2000)

Probing the structure and mechanism of binding of an inhibitor to a P-type-ATPase and of sugars during translocation by expressed transporters, using solid state MAS NMR.
di: Watts, A, et al.
Pubblicazione: (1998)

Galantamine-Curcumin Hybrids as Dual-Site Binding Acetylcholinesterase Inhibitors
di: Georgi Stavrakov, et al.
Pubblicazione: (2020-07-01)

Novel Triazole-Quinoline Derivatives as Selective Dual Binding Site Acetylcholinesterase Inhibitors
di: Susimaire P. Mantoani, et al.
Pubblicazione: (2016-02-01)

A model of reversible inhibitors in the gastric H+/K+-ATPase binding site determined by rotational echo double resonance NMR.
di: Watts, J, et al.
Pubblicazione: (2001)

Structural descriptions of ligands in their binding site of integral membrane proteins at near physiological conditions using solid-state NMR
di: Watts, A, et al.
Pubblicazione: (1998)

Novel Lawsone–Quinoxaline Hybrids as New Dual Binding Site Acetylcholinesterase Inhibitors
di: Paptawan Suwanhom, et al.
Pubblicazione: (2023-08-01)

Probing the agonist binding pocket in the nicotinic acetylcholine receptor: a high-resolution solid-state NMR approach.
di: Williamson, P, et al.
Pubblicazione: (1998)

Synthesis and evaluation of chromone-2-carboxamido-alkylamines as potent acetylcholinesterase inhibitors
di: Suwanhom, Paptawan, et al.
Pubblicazione: (2020)

Computer-Aided Discovery of Pentapeptide AEYTR as a Potent Acetylcholinesterase Inhibitor
di: Enade Perdana Istyastono, et al.
Pubblicazione: (2020-12-01)

Solid state NMR studies of ligand conformations in the binding sites of ion translocating APTases
di: Watts, J, et al.
Pubblicazione: (1999)

Hierarchical And Fragment Based Virtual Screening Approaches In The Discovery Of Potent Acetylcholinesterase Inhibitor
di: Muhammad, Erma Fatiha
Pubblicazione: (2022)

2-Benzoyl-6-benzylidenecyclohexanone analogs as potent dual inhibitors of acetylcholinesterase and butyrylcholinesterase
di: Sze, Wei Leong, et al.
Pubblicazione: (2016)

Solid state NMR studies of ligand dynamics and conformations is the binding sites of the gastric H+/K+-ATPase
di: Watts, J, et al.
Pubblicazione: (2000)

Acetylcholinesterase inhibitors with a thiazolium scaffold: structural features and binding modes
di: O. L. Kobzar, et al.
Pubblicazione: (2019-05-01)

Synthesis of 2‐(2‐oxo‐2 H ‐chromen‐4‐yl)acetamides as potent acetylcholinesterase inhibitors and molecular insights into binding interactions
di: Kara, Jiraporn, et al.
Pubblicazione: (2019)

Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors
di: Jong Min Oh, et al.
Pubblicazione: (2020-05-01)

In vitro and in vivo metabolism and inhibitory activities of vasicine, a potent acetylcholinesterase and butyrylcholinesterase inhibitor.
di: Wei Liu, et al.
Pubblicazione: (2015-01-01)

An Unusual Dimeric Inhibitor of Acetylcholinesterase: Cooperative Binding of Crystal Violet
di: Anders Allgardsson, et al.
Pubblicazione: (2017-08-01)

NMR observation of substrate in the binding site of an active sugar-H+ symport protein in native membranes.
di: Spooner, P, et al.
Pubblicazione: (1994)

Novel harmine derivatives as potent acetylcholinesterase and amyloid beta aggregation dual inhibitors for management of Alzheimer’s disease
di: Hongtao Du, et al.
Pubblicazione: (2023-12-01)

Detection of acetylcholinesterase activity and gamma-aminobutyric acid binding sites in Dicrocoelium dendriticum
di: Giménez-Pardo C., et al.
Pubblicazione: (2000-09-01)

Identification of the most potent acetylcholinesterase inhibitors from plants for possible treatment of Alzheimer’s disease: a computational approach
di: Bishajit Sarkar, et al.
Pubblicazione: (2021-02-01)

Imidazopyridazine Acetylcholinesterase Inhibitors Display Potent Anti-Proliferative Effects in the Human Neuroblastoma Cell-Line, IMR-32
di: Rakesh Kumar Sharma, et al.
Pubblicazione: (2021-09-01)

Structure guided development of potent reversibly binding penicillin binding protein inhibitors.
di: Woon, E, et al.
Pubblicazione: (2011)

Novichok Nerve Agents as Inhibitors of Acetylcholinesterase—In Silico Study of Their Non-Covalent Binding Affinity
di: Rafal Madaj, et al.
Pubblicazione: (2024-01-01)

Shifts in Backbone Conformation of Acetylcholinesterases upon Binding of Covalent Inhibitors, Reversible Ligands and Substrates
di: Zoran Radić
Pubblicazione: (2021-12-01)

Structural information on a membrane transport protein from nuclear magnetic resonance spectroscopy using sequence-selective nitroxide labeling.
di: Spooner, P, et al.
Pubblicazione: (1999)

Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes
di: Stane Pajk, et al.
Pubblicazione: (2020-01-01)

Dynamics in a protein-lipid complex: nuclear magnetic resonance measurements on the headgroup of cardiolipin when bound to cytochrome c.
di: Spooner, P, et al.
Pubblicazione: (1993)

Selective NMR observation of inhibitor and sugar binding to the galactose-H(+) symport protein GalP, of Escherichia coli.
di: Appleyard, A, et al.
Pubblicazione: (2000)

Possibility of Acetylcholinesterase Overexpression in Alzheimer Disease Patients after Therapy with Acetylcholinesterase Inhibitors
di: Alžběta Kračmarová, et al.
Pubblicazione: (2015-08-01)

Cryo-EM reveals an unprecedented binding site for NaV1.7 inhibitors enabling rational design of potent hybrid inhibitors
di: Marc Kschonsak, et al.
Pubblicazione: (2023-03-01)

Nuclear megnetic resonance in solids /
di: NATO Advanced Study Institute on Nuclear Magnetic Resonance in Solid (1974 : Leuven, Belgium), et al.
Pubblicazione: (1977)

Synthesis of Novel Chalcones as Acetylcholinesterase Inhibitors
di: Thanh-Dao Tran, et al.
Pubblicazione: (2016-07-01)

Natural sesquiterpen lactones as acetylcholinesterase inhibitors
di: HOMA HAJIMEHDIPOOR, et al.
Pubblicazione: (2014-06-01)

Membrane protein structure determination by solid state NMR.
di: Watts, A, et al.
Pubblicazione: (1999)

Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant
di: Gabriela Alves de Souza, et al.
Pubblicazione: (2019-01-01)

Identification of novel non-toxic and anti-angiogenic α-fluorinated chalcones as potent colchicine binding site inhibitors
di: Moran Sun, et al.
Pubblicazione: (2022-12-01)

Photochemical probe identification of a small-molecule inhibitor binding site in Hedgehog acyltransferase (HHAT)
di: Lanyon-Hogg, T, et al.
Pubblicazione: (2021)