A recent bottleneck of Y chromosome diversity coincides with a global change in culture

A recent bottleneck of Y chromosome diversity coincides with a global change in culture

It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50–100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying...

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मुख्य लेखकों: Karmin, M, Saag, L, Vicente, M, Sayres, MAW, Järve, M, Talas, UG, Rootsi, S, Ilumäe, A-M, Mägi, R, Mitt, M, Pagani, L, Puurand, T, Faltyskova, Z, Clemente, F, Cardona, A, Metspalu, E, Sahakyan, H, Yunusbayev, B, Hudjashov, G, Degiorgio, M, Loogväli, E-L, Eichstaedt, C, Eelmets, M, Chaubey, G, Tambets, K, Litvinov, S, Mormina, M, Xue, Y, Ayub, Q, Zoraqi, G, Korneliussen, TS, Akhatova, F, Lachance, J, Tishkoff, S, Momynaliev, K, Ricaut, F-X, Kusuma, P, Razafindrazaka, H, Pierron, D, Cox, MP, Sultana, GNN, Willerslev, R, Muller, C, Westaway, M, Lambert, D, Skaro, V, Kovačevic´, L, Turdikulova, S, Dalimova, D, Khusainova, R, Trofimova, N, Akhmetova, V, Khidiyatova, I, Lichman, DV, Isakova, J, Pocheshkhova, E, Sabitov, Z, Barashkov, NA, Nymadawa, P, Mihailov, E, Seng, JWT, Evseeva, I, Migliano, AB, Abdullah, S, Andriadze, G, Primorac, D, Atramentova, L, Utevska, O, Yepiskoposyan, L, Marjanovic´, D, Kushniarevich, A, Behar, DM, Gilissen, C, Vissers, L, Veltman, JA, Balanovska, E, Derenko, M, Malyarchuk, B, Metspalu, A, Fedorova, S, Eriksson, A, Manica, A, Mendez, FL, Karafet, TM, Veeramah, KR, Bradman, N, Hammer, MF, Osipova, LP, Balanovsky, O, Khusnutdinova, EK, Johnsen, K, Remm, M, Thomas, MG, Tyler-Smith, C, Underhill, PA, Willerslev, E, Nielsen, R, Metspalu, M, Villems, R, Kivisild, T
स्वरूप: Journal article
भाषा:English
प्रकाशित: Cold Spring Harbor Laboratory Press 2015
विवरण
सारांश:It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50–100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, we date the Y-chromosomal most recent common ancestor (MRCA) in Africa at 254 (95% CI 192–307) kya and detect a cluster of major non-African founder haplogroups in a narrow time interval at 47–52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.

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