Rab GEFs and GAPs.
Rabs are GTP-binding proteins with conserved functions in membrane trafficking. They are regulated by a diverse group of structurally unrelated GDP-GTP exchange factors (GEFs), and a family of GTP-hydrolysis activating proteins (GAPs) containing the conserved TBC domain. Recent structural and cell b...
| Үндсэн зохиолчид: | , |
|---|---|
| Формат: | Journal article |
| Хэл сонгох: | English |
| Хэвлэсэн: |
2010
|
| _version_ | 1826290017903837184 |
|---|---|
| author | Barr, F Lambright, D |
| author_facet | Barr, F Lambright, D |
| author_sort | Barr, F |
| collection | OXFORD |
| description | Rabs are GTP-binding proteins with conserved functions in membrane trafficking. They are regulated by a diverse group of structurally unrelated GDP-GTP exchange factors (GEFs), and a family of GTP-hydrolysis activating proteins (GAPs) containing the conserved TBC domain. Recent structural and cell biological studies shed new light on the mechanisms of Rab GEF and GAP action, and the cellular trafficking pathways they act in. |
| first_indexed | 2024-03-07T02:37:46Z |
| format | Journal article |
| id | oxford-uuid:a95ac65c-ecf9-401b-8dba-c67e525319f0 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:37:46Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:a95ac65c-ecf9-401b-8dba-c67e525319f02022-03-27T03:08:00ZRab GEFs and GAPs.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a95ac65c-ecf9-401b-8dba-c67e525319f0EnglishSymplectic Elements at Oxford2010Barr, FLambright, DRabs are GTP-binding proteins with conserved functions in membrane trafficking. They are regulated by a diverse group of structurally unrelated GDP-GTP exchange factors (GEFs), and a family of GTP-hydrolysis activating proteins (GAPs) containing the conserved TBC domain. Recent structural and cell biological studies shed new light on the mechanisms of Rab GEF and GAP action, and the cellular trafficking pathways they act in. |
| spellingShingle | Barr, F Lambright, D Rab GEFs and GAPs. |
| title | Rab GEFs and GAPs. |
| title_full | Rab GEFs and GAPs. |
| title_fullStr | Rab GEFs and GAPs. |
| title_full_unstemmed | Rab GEFs and GAPs. |
| title_short | Rab GEFs and GAPs. |
| title_sort | rab gefs and gaps |
| work_keys_str_mv | AT barrf rabgefsandgaps AT lambrightd rabgefsandgaps |