Entropy-driven genome organization.
DNA and RNA polymerases active on bacterial and human genomes in the crowded environment of a cell are modeled as beads spaced along a string. Aggregation of the large polymerizing complexes increases the entropy of the system through an increase in entropy of the many small crowding molecules; this...
Main Authors: | Marenduzzo, D, Micheletti, C, Cook, P |
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Format: | Journal article |
Language: | English |
Published: |
2006
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