Strategies for antigen choice and priming of dendritic cells influence the polarization and efficacy of antitumor T-cell responses in dendritic cell-based cancer vaccination.
Dendritic cells (DCs) primed with tumor antigens (Ags) can stimulate tumor rejection. This study was aimed at evaluating the polarization of T-cell responses using various DC Ag-priming strategies for vaccination purposes. DCs cocultured with irradiated "apoptotic" tumor cells, DC-tumor fu...
Main Authors: | Galea-Lauri, J, Wells, J, Darling, D, Harrison, P, Farzaneh, F |
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Format: | Journal article |
Language: | English |
Published: |
2004
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