The effects of malaria chemoprophylaxis given by traditional birth attendants on the course and outcome of pregnancy.

A trial of malaria chemoprophylaxis given by traditional birth attendants was undertaken in a rural area of The Gambia where access to antenatal clinics is difficult. Women received one or more doses of Maloprim or placebo from a traditional birth attendant during 1049 of 1208 pregnancies (87%) reco...

Full description

Bibliographic Details
Main Authors: Greenwood, B, Greenwood, A, Snow, R, Byass, P, Bennett, S, Hatib-N'Jie, AB
Format: Journal article
Language:English
Published: 1989
_version_ 1826290110402920448
author Greenwood, B
Greenwood, A
Snow, R
Byass, P
Bennett, S
Hatib-N'Jie, AB
author_facet Greenwood, B
Greenwood, A
Snow, R
Byass, P
Bennett, S
Hatib-N'Jie, AB
author_sort Greenwood, B
collection OXFORD
description A trial of malaria chemoprophylaxis given by traditional birth attendants was undertaken in a rural area of The Gambia where access to antenatal clinics is difficult. Women received one or more doses of Maloprim or placebo from a traditional birth attendant during 1049 of 1208 pregnancies (87%) recorded in 16 villages over a 3-year period. Primigravidae who received Maloprim had a lower parasite rate and a significantly higher mean packed cell volume than primigravidae who received placebo, and their babies were significantly heavier (6% low birth weight vs 22%). In multigravidae chemoprophylaxis reduced malaria parasitaemia but it had no beneficial effect on haemoglobin level and much less effect on birth weight than was observed in primigravidae. However, the mean birth weight of babies born to grandemultigravidae who received chemoprophylaxis was significantly higher than that of babies born to grandemultigravidae who did not.
first_indexed 2024-03-07T02:39:10Z
format Journal article
id oxford-uuid:a9da5777-2560-4e76-8235-15f4edc468cd
institution University of Oxford
language English
last_indexed 2024-03-07T02:39:10Z
publishDate 1989
record_format dspace
spelling oxford-uuid:a9da5777-2560-4e76-8235-15f4edc468cd2022-03-27T03:11:05ZThe effects of malaria chemoprophylaxis given by traditional birth attendants on the course and outcome of pregnancy.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a9da5777-2560-4e76-8235-15f4edc468cdEnglishSymplectic Elements at Oxford1989Greenwood, BGreenwood, ASnow, RByass, PBennett, SHatib-N'Jie, ABA trial of malaria chemoprophylaxis given by traditional birth attendants was undertaken in a rural area of The Gambia where access to antenatal clinics is difficult. Women received one or more doses of Maloprim or placebo from a traditional birth attendant during 1049 of 1208 pregnancies (87%) recorded in 16 villages over a 3-year period. Primigravidae who received Maloprim had a lower parasite rate and a significantly higher mean packed cell volume than primigravidae who received placebo, and their babies were significantly heavier (6% low birth weight vs 22%). In multigravidae chemoprophylaxis reduced malaria parasitaemia but it had no beneficial effect on haemoglobin level and much less effect on birth weight than was observed in primigravidae. However, the mean birth weight of babies born to grandemultigravidae who received chemoprophylaxis was significantly higher than that of babies born to grandemultigravidae who did not.
spellingShingle Greenwood, B
Greenwood, A
Snow, R
Byass, P
Bennett, S
Hatib-N'Jie, AB
The effects of malaria chemoprophylaxis given by traditional birth attendants on the course and outcome of pregnancy.
title The effects of malaria chemoprophylaxis given by traditional birth attendants on the course and outcome of pregnancy.
title_full The effects of malaria chemoprophylaxis given by traditional birth attendants on the course and outcome of pregnancy.
title_fullStr The effects of malaria chemoprophylaxis given by traditional birth attendants on the course and outcome of pregnancy.
title_full_unstemmed The effects of malaria chemoprophylaxis given by traditional birth attendants on the course and outcome of pregnancy.
title_short The effects of malaria chemoprophylaxis given by traditional birth attendants on the course and outcome of pregnancy.
title_sort effects of malaria chemoprophylaxis given by traditional birth attendants on the course and outcome of pregnancy
work_keys_str_mv AT greenwoodb theeffectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT greenwooda theeffectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT snowr theeffectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT byassp theeffectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT bennetts theeffectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT hatibnjieab theeffectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT greenwoodb effectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT greenwooda effectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT snowr effectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT byassp effectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT bennetts effectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy
AT hatibnjieab effectsofmalariachemoprophylaxisgivenbytraditionalbirthattendantsonthecourseandoutcomeofpregnancy