Structural studies of Norrin dependent Wnt/beta-catenin signaling
<p>Norrin is a secreted cystine-knot growth factor that plays critical roles in vascular development in the brain, retina, and cochlea, as well as the uterus. Although Norrin is unrelated to the lipid-modified morphogens Wnts, Norrin activates the canonical Wnt/β-catenin pathway by binding to...
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| Format: | Thesis |
| Sprog: | English |
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2014
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