New genes in inflammatory bowel disease: lessons for complex diseases?
<p style="text-align:justify;"> The chronic inflammatory bowel diseases Crohn's disease and ulcerative colitis are common causes of gastrointestinal disease in northern Europe, affecting as many as one in 250 people. Although mortality is low, morbidity associated with these di...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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Elsevier
2006
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| _version_ | 1826290144747978752 |
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| author | Gaya, DR Russell, RK Nimmo, ER Satsangi, J |
| author_facet | Gaya, DR Russell, RK Nimmo, ER Satsangi, J |
| author_sort | Gaya, DR |
| collection | OXFORD |
| description | <p style="text-align:justify;"> The chronic inflammatory bowel diseases Crohn's disease and ulcerative colitis are common causes of gastrointestinal disease in northern Europe, affecting as many as one in 250 people. Although mortality is low, morbidity associated with these diseases is substantial. We review the recent advances in the genetics of inflammatory bowel disease, with particular emphasis on the data that have been generated since the discovery of the CARD15 (NOD2) gene in 2001. </p> |
| first_indexed | 2024-03-07T02:39:42Z |
| format | Journal article |
| id | oxford-uuid:aa02f388-9148-4847-9080-38bfc6c08154 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:39:42Z |
| publishDate | 2006 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:aa02f388-9148-4847-9080-38bfc6c081542022-03-27T03:12:18ZNew genes in inflammatory bowel disease: lessons for complex diseases?Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:aa02f388-9148-4847-9080-38bfc6c08154EnglishSymplectic Elements at OxfordElsevier2006Gaya, DRRussell, RKNimmo, ERSatsangi, J <p style="text-align:justify;"> The chronic inflammatory bowel diseases Crohn's disease and ulcerative colitis are common causes of gastrointestinal disease in northern Europe, affecting as many as one in 250 people. Although mortality is low, morbidity associated with these diseases is substantial. We review the recent advances in the genetics of inflammatory bowel disease, with particular emphasis on the data that have been generated since the discovery of the CARD15 (NOD2) gene in 2001. </p> |
| spellingShingle | Gaya, DR Russell, RK Nimmo, ER Satsangi, J New genes in inflammatory bowel disease: lessons for complex diseases? |
| title | New genes in inflammatory bowel disease: lessons for complex diseases? |
| title_full | New genes in inflammatory bowel disease: lessons for complex diseases? |
| title_fullStr | New genes in inflammatory bowel disease: lessons for complex diseases? |
| title_full_unstemmed | New genes in inflammatory bowel disease: lessons for complex diseases? |
| title_short | New genes in inflammatory bowel disease: lessons for complex diseases? |
| title_sort | new genes in inflammatory bowel disease lessons for complex diseases |
| work_keys_str_mv | AT gayadr newgenesininflammatoryboweldiseaselessonsforcomplexdiseases AT russellrk newgenesininflammatoryboweldiseaselessonsforcomplexdiseases AT nimmoer newgenesininflammatoryboweldiseaselessonsforcomplexdiseases AT satsangij newgenesininflammatoryboweldiseaselessonsforcomplexdiseases |