Current practice in methodology and reporting of the sample size calculation in randomised trials of hip and knee osteoarthritis: a systematic review

This study aims to review the methodology and reporting of sample size calculation in a contemporary sample of hip and knee osteoarthritis trials. The choice of sample size is a key aspect of designing a clinical trial, ensuring that the trial is powered to detect clinically important treatment effe...

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Main Authors: Copsey, B, Thompson, J, Vadher, K, Ali, U, Dutton, S, Fitzpatrick, R, Lamb, S, Cook, J
Format: Conference item
Published: Elsevier 2018
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author Copsey, B
Thompson, J
Vadher, K
Ali, U
Dutton, S
Fitzpatrick, R
Lamb, S
Cook, J
author_facet Copsey, B
Thompson, J
Vadher, K
Ali, U
Dutton, S
Fitzpatrick, R
Lamb, S
Cook, J
author_sort Copsey, B
collection OXFORD
description This study aims to review the methodology and reporting of sample size calculation in a contemporary sample of hip and knee osteoarthritis trials. The choice of sample size is a key aspect of designing a clinical trial, ensuring that the trial is powered to detect clinically important treatment effects, is ethically sound and does not overuse resources. Accurate and complete reporting of the sample size calculation allows the reader to interpret the trial results alongside the aims and assumptions made when the trial was designed.
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spelling oxford-uuid:aa04b914-403d-46df-afd1-21ffa88b2bdc2022-03-27T03:12:19ZCurrent practice in methodology and reporting of the sample size calculation in randomised trials of hip and knee osteoarthritis: a systematic reviewConference itemhttp://purl.org/coar/resource_type/c_c94fuuid:aa04b914-403d-46df-afd1-21ffa88b2bdcSymplectic Elements at OxfordElsevier2018Copsey, BThompson, JVadher, KAli, UDutton, SFitzpatrick, RLamb, SCook, JThis study aims to review the methodology and reporting of sample size calculation in a contemporary sample of hip and knee osteoarthritis trials. The choice of sample size is a key aspect of designing a clinical trial, ensuring that the trial is powered to detect clinically important treatment effects, is ethically sound and does not overuse resources. Accurate and complete reporting of the sample size calculation allows the reader to interpret the trial results alongside the aims and assumptions made when the trial was designed.
spellingShingle Copsey, B
Thompson, J
Vadher, K
Ali, U
Dutton, S
Fitzpatrick, R
Lamb, S
Cook, J
Current practice in methodology and reporting of the sample size calculation in randomised trials of hip and knee osteoarthritis: a systematic review
title Current practice in methodology and reporting of the sample size calculation in randomised trials of hip and knee osteoarthritis: a systematic review
title_full Current practice in methodology and reporting of the sample size calculation in randomised trials of hip and knee osteoarthritis: a systematic review
title_fullStr Current practice in methodology and reporting of the sample size calculation in randomised trials of hip and knee osteoarthritis: a systematic review
title_full_unstemmed Current practice in methodology and reporting of the sample size calculation in randomised trials of hip and knee osteoarthritis: a systematic review
title_short Current practice in methodology and reporting of the sample size calculation in randomised trials of hip and knee osteoarthritis: a systematic review
title_sort current practice in methodology and reporting of the sample size calculation in randomised trials of hip and knee osteoarthritis a systematic review
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