Phosphorylation and dephosphorylation regulate the Fanconi anaemia DNA repair pathway
Interstrand crosslink (ICL) is a highly deleterious form of DNA damage as crosslinked DNA double strands block DNA replication, transcription machinery and prevent chromosome segregation. One of the major pathways for resolving DNA ICL damage is the Fanconi anaemia (FA) pathway, of which recruitment...
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| Format: | Thesis |
| Language: | English |
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2023
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