Adenovirus-mediated gene transfer of CTLA-4Ig fusion protein in the suppression of experimental autoimmune arthritis.

Adenovirus-mediated gene transfer of CTLA-4Ig fusion protein in the suppression of experimental autoimmune arthritis.

OBJECTIVE: Blockade of CD28-B7 interactions with soluble CTLA-4Ig fusion protein (which binds and blocks both B7-1 and B7-2 costimulatory molecules on antigen-presenting cells) has been shown to ameliorate experimental autoimmune diseases such as lupus, experimental autoimmune encephalomyelitis, di...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Quattrocchi, E, Dallman, M, Feldmann, M
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2000

समान संसाधन

[Recombinant adenovirus-mediated gene transfer suppresses experimental arthritis]
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