Limited polymorphism in the dihydrofolate reductase (dhfr) and dihydropteroate synthase genes (dhps) of Plasmodium knowlesi isolate from Thailand

Limited polymorphism in the dihydrofolate reductase (dhfr) and dihydropteroate synthase genes (dhps) of Plasmodium knowlesi isolate from Thailand

<p><i>Background:</i> The 2022 malaria WHO reported around 4000 <i>P. knowlesi</i> infections in the South-East Asia region. In the same period, 72 positive cases were reported by the Department of Disease Control in Thailand, suggesting a persistent infection. Little i...

Full description

Bibliographic Details
Main Authors:	Sangsri, R, Choowongkomon, K, Tuntipaiboontana, R, Sugaram, R, Boondej, P, Sudathip, P, Dondorp, AM, Imwong, M
Format:	Journal article
Language:	English
Published:	Elsevier 2023

Similar Items

Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries
by: Tanomsing, N, et al.
Published: (2014)

Genetic variability of Plasmodium malariae dihydropteroate synthase (dhps) in four Asian countries.
by: Naowarat Tanomsing, et al.
Published: (2014-01-01)

Genetic population of Plasmodium knowlesi during pre-malaria elimination in Thailand
by: Sugaram, R, et al.
Published: (2021)

Limited polymorphism in the dihydropteroate synthetase gene (dhps) of Plasmodium vivax isolates from Thailand.
by: Imwong, M, et al.
Published: (2005)

Comparative study between DHFR and DHPS genes in Plasmodium falciparum Plasmodium vivax and Plasmodium knowlesi isolated from Sabah
by: Nor Afizah Nuin
Published: (2016)

Isolation of Lactobacillus and Enzymatic Activity of Dihydrofolate Reductase (DHFR) in Musa spp.
by: Afira Waqar, et al.
Published: (2024-01-01)

Cloning and heterologous expression of Plasmodium ovale dihydrofolate reductase-thymidylate synthase gene
by: Tirakarn, S, et al.
Published: (2012)

Cloning and heterologous expression of Plasmodium ovale dihydrofolate reductase-thymidylate synthase gene.
by: Tirakarn, S, et al.
Published: (2012)

Analysis of Mutations in Pneumocystis jirovecii Dihydropteroate Synthase and Dihydropteroate Reductase Genes Among Non-HIV Patients in China
by: Wu Y, et al.
Published: (2024-12-01)

Hybrid-drug design targeting pseudomonas aeruginosa DHPS and DHFR
by: Jayaraman, Premkumar, et al.
Published: (2014)

Geographic distribution of amino acid mutations in DHFR and DHPS in Plasmodium vivax isolates from Lao PDR, India and Colombia
by: Saralamba, N, et al.
Published: (2016)

Computational analysis of binding between malarial dihydrofolate reductases and anti-folates.
by: Choowongkomon, K, et al.
Published: (2010)

Computational analysis of binding between malarial dihydrofolate reductases and anti-folates
by: Choowongkomon, K, et al.
Published: (2010)

Accurate and sensitive detection of Plasmodium species in humans by use of the dihydrofolate reductase-thymidylate synthase linker region.
by: Tanomsing, N, et al.
Published: (2010)

Genetic analysis of the dihydrofolate reductase-thymidylate synthase gene from geographically diverse isolates of Plasmodium malariae.
by: Tanomsing, N, et al.
Published: (2007)

GENETIC ANALYSIS OF THE DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE GENE FROM GEOGRAPHICALLY DIVERSE ISOLATES OF PLASMODIUM MALARIAE
by: Tanomsing, N, et al.
Published: (2008)

Frequencies distribution of dihydrofolate reductase and dihydropteroate synthetase mutant alleles associated with sulfadoxine-pyrimethamine resistance in Plasmodium falciparum population from Hadhramout Governorate, Yemen
by: Bamaga, O.A.A., et al.
Published: (2015)

Dihydrofolate-reductase mutations in Plasmodium knowlesi appear unrelated to selective drug pressure from putative human-to-human transmission in Sabah, Malaysia
by: Grigg, MJ, et al.
Published: (2016)

Dihydrofolate-reductase mutations in Plasmodium knowlesi appear unrelated to selective drug pressure from putative human-to-human transmission in Sabah, Malaysia
by: Yeo, Tsin Wen, et al.
Published: (2018)

Molecular docking of various anti-malarial agents against malarial dihydrofolate reductase (DHFR) enzymen using open source software /
by: Syarifah Nurul Ain Syed Yahya, 1987-, et al.
Published: (2008)

Molecular characterization of dihydrofolate reductase in relation to antifolate resistance in Plasmodium vivax.
by: Leartsakulpanich, U, et al.
Published: (2002)

Evaluation of Antimalarial Activity of Sesquiterpene Lactones of Wild Sudanese Basil (Ocimum basilicum L.) through their in vitro Inhibition of Dihydrofolate Reductase (DHFR)
by: Elhussein, Salah Ahmed, et al.
Published: (2015)

The binding of trimethoprim to bacterial dihydrofolate reductase.
by: Baker, D, et al.
Published: (1981)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.
by: Crabtree, M, et al.
Published: (2011)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
by: Crabtree, M, et al.
Published: (2011)

Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase.
by: Achari, A, et al.
Published: (1997)

Dihydrofolate reductase and biopterin recycling in cardiovascular disease.
by: Crabtree, M, et al.
Published: (2009)

Preliminary crystallographic data for Pneumocystis carinii dihydrofolate reductase.
by: Stammers, D, et al.
Published: (1993)

Docking of anti-malarial drug derivatives into Plasmodium Vivax dihydrofolate reductase /
by: Wong, Bing Ming, 1986-, et al.
Published: (2009)

Novel point mutations in the dihydrofolate reductase gene of Plasmodium vivax: evidence for sequential selection by drug pressure.
by: Imwong, M, et al.
Published: (2003)

Refolding of recombinant Pneumocystis carinii dihydrofolate reductase and characterization of the enzyme.
by: Delves, C, et al.
Published: (1993)

Resistance of <i>Wolbachia</i> to Trimethoprim: Insights into Genes Encoding Dihydrofolate Reductase, Thymidylate Synthase and Serine Hydroxymethyltransferase in the Rickettsiales
by: Ann M. Fallon
Published: (2024-12-01)

The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution.
by: Champness, J, et al.
Published: (1994)

The structure of Pneumocystis carinii dihydrofolate reductase to 1.9 A resolution.
by: Champness, J, et al.
Published: (1994)

Computational identification of candidate inhibitors for Dihydrofolate reductase in Acinetobacter baumannii
by: Saurabh Kumar Bhati, et al.
Published: (2024-01-01)

ONT sequencing identifies a high prevalence of crt sensitive, triple mutant dhfr and single mutant dhps parasites within an ANC population in Nigeria
by: Adebanjo Jonathan Adegbola, et al.
Published: (2024-10-01)

FtsH degrades dihydrofolate reductase by recognizing a partially folded species
by: Morehouse, Juhee P., et al.
Published: (2022)

Cymoxanil disrupts RNA synthesis through inhibiting the activity of dihydrofolate reductase
by: Thomas David Daniel Kazmirchuk, et al.
Published: (2024-05-01)

Dihydrofolate reductase mutations in Plasmodium vivax from Indonesia and therapeutic response to sulfadoxine plus pyrimethamine.
by: Hastings, MD, et al.
Published: (2004)

Advancing artemisinin resistance monitoring using a high sensitivity ddPCR assay for Pfkelch13 mutation detection in Asia
by: Srisutham, S, et al.
Published: (2025)