Presence and pathogenic relevance of antibodies to clustered acetylcholine receptor in ocular and generalized myasthenia gravis.

BACKGROUND: Clustered acetylcholine receptor antibodies (clustered AChR-Abs) have been detected in a proportion of patients with previously "seronegative" (SN) generalized myasthenia gravis (GMG), but their presence in patients with ocular MG (OMG) and their pathogenicity in vivo are unkn...

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Hlavní autoři: Jacob, S, Viegas, S, Leite, M, Webster, R, Cossins, J, Kennett, R, Hilton-Jones, D, Morgan, B, Vincent, A
Médium: Journal article
Jazyk:English
Vydáno: 2012