Interleukin 13 (IL-13)-regulated expression of the chondroprotective metalloproteinase ADAM15 is reduced in aging cartilage
Objective<br> The adamalysin metalloproteinase 15 (ADAM15) has been shown to protect against development of osteoarthritis in mice. Here, we have investigated factors that control ADAM15 levels in cartilage. <br> Design<br> Secretomes from wild-type and Adam15−/− chondrocytes were...
Main Authors: | Yang, CY, Chanalaris, A, Bonelli, S, McClurg, O, Hiles, GL, Cates, AL, Zarebska, JM, Vincent, TL, Day, ML, Müller, SA, Lichtenthaler, SF, Nagase, H, Troeberg, L, Scilabra, SD |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2020
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