Maturation of the human immunoglobulin heavy chain repertoire with age
B cells play a central role in adaptive immune processes, mainly through the production of antibodies. The maturation of the B cell system with age is poorly studied. We extensively investigated age-related alterations of naïve and antigen-experienced immunoglobulin heavy chain (IgH) repertoires. Th...
المؤلفون الرئيسيون: | , , , , , , , , , , |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Frontiers Media
2020
|