Maturation of the human immunoglobulin heavy chain repertoire with age

B cells play a central role in adaptive immune processes, mainly through the production of antibodies. The maturation of the B cell system with age is poorly studied. We extensively investigated age-related alterations of naïve and antigen-experienced immunoglobulin heavy chain (IgH) repertoires. Th...

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מידע ביבליוגרפי
Main Authors: Ghraichy, M, Galson, JD, Kovaltsuk, A, von Niederhäusern, V, Pachlopnik Schmid, J, Recher, M, Jauch, AJ, Miho, E, Kelly, DF, Deane, CM, Trück, J
פורמט: Journal article
שפה:English
יצא לאור: Frontiers Media 2020