Role of interleukin-1beta in postoperative cognitive dysfunction.
OBJECTIVE: Although postoperative cognitive dysfunction (POCD) often complicates recovery from major surgery, the pathogenic mechanisms remain unknown. We explored whether systemic inflammation, in response to surgical trauma, triggers hippocampal inflammation and subsequent memory impairment, in a...
Main Authors: | Cibelli, M, Fidalgo, A, Terrando, N, Ma, D, Monaco, C, Feldmann, M, Takata, M, Lever, I, Nanchahal, J, Fanselow, MS, Maze, M |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2010
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