BNIP3 expression is linked with hypoxia-regulated protein expression and with poor prognosis in non-small cell lung cancer.

BNIP3 is a proapoptotic protein regulated by hypoxia-inducible factor 1. We analyzed BNIP3 expression in 105 tumor samples from early operable, non-small lung cancer and the relationship of expression to hypoxia-inducible factor 1alpha, other hypoxia-regulated pathways, and prognosis. There was stro...

Full description

Bibliographic Details
Main Authors: Giatromanolaki, A, Koukourakis, M, Sowter, H, Sivridis, E, Gibson, S, Gatter, K, Harris, A
Format: Journal article
Language:English
Published: 2004