RAPTOR up-regulation contributes to resistance of renal cancer cells to PI3K-mTOR inhibition PONE-D-17-28641
The outlook for patients with advanced renal cell cancer (RCC) has been improved by targeted agents including inhibitors of the PI3 kinase (PI3K)-AKT-mTOR axis, although treatment resistance is a major problem. Here, we aimed to understand how RCC cells acquire resistance to PI3K-mTOR inhibition. W...
| Hlavní autoři: | , , , , , |
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| Médium: | Journal article |
| Vydáno: |
Public Library of Science
2018
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