Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults.
Obesity is associated with increased cardiovascular risk. Anthropometric cut-off values derived for Caucasians may not be applicable to other populations. The main objective of the present study was to derive population-specific anthropometric cut-off values to define high CVD risk for Sri Lankan ad...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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2011
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| _version_ | 1797087813590581248 |
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| author | Katulanda, P Jayawardena, M Sheriff, M Matthews, DR |
| author_facet | Katulanda, P Jayawardena, M Sheriff, M Matthews, DR |
| author_sort | Katulanda, P |
| collection | OXFORD |
| description | Obesity is associated with increased cardiovascular risk. Anthropometric cut-off values derived for Caucasians may not be applicable to other populations. The main objective of the present study was to derive population-specific anthropometric cut-off values to define high CVD risk for Sri Lankan adults. A nationally representative sample of 4474 non-institutionalised adults aged ≥ 18 years was analysed. Cut-off values to provide optimum sensitivity and specificity were derived using receiver-operating characteristic curve analysis. BMI, waist circumference (WC), waist-to-hip ratio (WHR), blood pressure and overnight fasting venous blood samples were collected to measure glucose, HDL-cholesterol and TAG. An oral glucose tolerance test was also performed. The results suggested that the age-adjusted BMI, WC and WHR were significantly associated with all cardiovascular risk factors (P < 0·001). Cut-off values for BMI, WC and WHR for males were 20·7 kg/m2, 76·5 cm and 0·89, respectively. The respective values for females were 22·0 kg/m2, 76·3 cm and 0·85. The common cut-off value for BMI for males and females was 21·5 kg/m2. Similarly, WC and WHR cut-off values for both males and females were 76·3 cm and 0·87, respectively. The Asian and Caucasian anthropometric cut-off levels showed lower sensitivity and higher false negative percentage compared with newly derived cut-off levels. In conclusion, BMI, WC and WHR were all associated with increased CVD risk. We propose the following anthropometric cut-off points to determine high CVD risk level for Sri Lankan adults: BMI ≥ 21·5 kg/m2, WC ≥ 76 cm and WHR ≥ 0·85 (women) and 0·90 (men). |
| first_indexed | 2024-03-07T02:41:02Z |
| format | Journal article |
| id | oxford-uuid:aa775814-5aae-4c57-a857-58bf13a21fcd |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:41:02Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | oxford-uuid:aa775814-5aae-4c57-a857-58bf13a21fcd2022-03-27T03:15:15ZDerivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:aa775814-5aae-4c57-a857-58bf13a21fcdEnglishSymplectic Elements at Oxford2011Katulanda, PJayawardena, MSheriff, MMatthews, DRObesity is associated with increased cardiovascular risk. Anthropometric cut-off values derived for Caucasians may not be applicable to other populations. The main objective of the present study was to derive population-specific anthropometric cut-off values to define high CVD risk for Sri Lankan adults. A nationally representative sample of 4474 non-institutionalised adults aged ≥ 18 years was analysed. Cut-off values to provide optimum sensitivity and specificity were derived using receiver-operating characteristic curve analysis. BMI, waist circumference (WC), waist-to-hip ratio (WHR), blood pressure and overnight fasting venous blood samples were collected to measure glucose, HDL-cholesterol and TAG. An oral glucose tolerance test was also performed. The results suggested that the age-adjusted BMI, WC and WHR were significantly associated with all cardiovascular risk factors (P < 0·001). Cut-off values for BMI, WC and WHR for males were 20·7 kg/m2, 76·5 cm and 0·89, respectively. The respective values for females were 22·0 kg/m2, 76·3 cm and 0·85. The common cut-off value for BMI for males and females was 21·5 kg/m2. Similarly, WC and WHR cut-off values for both males and females were 76·3 cm and 0·87, respectively. The Asian and Caucasian anthropometric cut-off levels showed lower sensitivity and higher false negative percentage compared with newly derived cut-off levels. In conclusion, BMI, WC and WHR were all associated with increased CVD risk. We propose the following anthropometric cut-off points to determine high CVD risk level for Sri Lankan adults: BMI ≥ 21·5 kg/m2, WC ≥ 76 cm and WHR ≥ 0·85 (women) and 0·90 (men). |
| spellingShingle | Katulanda, P Jayawardena, M Sheriff, M Matthews, DR Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults. |
| title | Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults. |
| title_full | Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults. |
| title_fullStr | Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults. |
| title_full_unstemmed | Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults. |
| title_short | Derivation of anthropometric cut-off levels to define CVD risk in Sri Lankan adults. |
| title_sort | derivation of anthropometric cut off levels to define cvd risk in sri lankan adults |
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