Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination

<p><strong>Background:</strong> Development of an effective vaccine against the pathogenic blood-stage infection of human malaria has proved challenging, and no candidate vaccine has affected blood-stage parasitemia following controlled human malaria infection (CHMI) with blood-sta...

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Hlavní autoři: Minassian, AM, Silk, SE, Barrett, JR, Nielsen, CM, Miura, K, Diouf, A, Loos, C, Fallon, JK, Michell, AR, White, MT, Edwards, NJ, Poulton, ID, Mitton, CH, Payne, RO, Marks, M, Maxwell-Scott, H, Querol-Rubiera, A, Bisnauthsing, K, Batra, R, Ogrina, T, Brendish, NJ, Themistocleous, Y, Rawlinson, TA, Ellis, KJ, Quinkert, D, Baker, M, Lopez Ramon, R, Ramos Lopez, F, Barfod, L, Folegatti, PM, Silman, D, Datoo, M, Taylor, IJ, Jin, J, Pulido, D, Douglas, AD, de Jongh, WA, Smith, R, Berrie, E, Noe, AR, Diggs, CL, Soisson, LA, Ashfield, R, Faust, SN, Goodman, AL, Lawrie, AM, Nugent, FL, Alter, G, Long, CA, Draper, SJ
Médium: Journal article
Jazyk:English
Vydáno: Cell Press 2021