The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells

The only currently available approach to early efficacy testing of tuberculosis (TB) vaccine candidates is in vivo preclinical challenge models. These typically include mice, guinea pigs and non-human primates (NHPs), which must be exposed to virulent M.tb in a ‘challenge’ experiment following vacci...

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Үндсэн зохиолчид: Tanner, R, Hoogkamer, E, Bitencourt, J, White, A, Boot, C, Sombroek, CC, Harris, SA, O'Shea, MK, Wright, D, Wittenberg, R, Sarfas, C, Satti, I, Verreck, FAW, Sharpe, SA, Fletcher, HA, McShane, H
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: F1000Research 2021

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