Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice
Sarcomere assembly is a highly orchestrated and dynamic process which adapts, during perinatal development, to accommodate growth of the heart. Sarcomeric components, including titin, undergo an isoform transition to adjust ventricular filling. Many sarcomeric genes have been implicated in congenita...
Main Authors: | Smart, N, Riegler, J, Turtle, C, Lygate, C, McAndrew, D, Gehmlich, K, Dubé, K, Price, A, Muthurangu, V, Taylor, A, Redwood, C, Riley, P |
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Format: | Journal article |
Published: |
Elsevier
2016
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