Endpoints for clinical trials evaluating disease modification and structural damage in adults with Crohn's disease.

The management of Crohn's disease is rapidly changing. The advent of potent immunomodulatory and biologic therapies has led to more demanding endpoints for clinical trials than only clinical response and remission. Complete withdrawal of corticosteroids, healing of endoscopically visible lesion...

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Main Authors: D'Haens, G, Fedorak, R, Lémann, M, Feagan, BG, Kamm, M, Cosnes, J, Rutgeerts, P, Marteau, P, Travis, S, Schölmerich, J, Hanauer, S, Sandborn, W
格式: Journal article
语言:English
出版: 2009