Splenic phagocytic function in patients with inflammatory bowel disease.

Splenic phagocytic function has been assessed in patients with inflammatory bowel disease. No Howell-Jolly bodies were found on blood film examination. Slow clearance times of heat damaged red cells were found in 13 of 16 patients with ulcerative colitis compared with 4 of 17 patients with Crohn...

Popoln opis

Bibliografske podrobnosti
Main Authors: Jewell, D, Berney, J, Pettit, J
Format: Journal article
Jezik:English
Izdano: Informa Healthcare 1981
_version_ 1826290256986505216
author Jewell, D
Berney, J
Pettit, J
author_facet Jewell, D
Berney, J
Pettit, J
author_sort Jewell, D
collection OXFORD
description Splenic phagocytic function has been assessed in patients with inflammatory bowel disease. No Howell-Jolly bodies were found on blood film examination. Slow clearance times of heat damaged red cells were found in 13 of 16 patients with ulcerative colitis compared with 4 of 17 patients with Crohn's disease (P less than 0.01). For ulcerative colitis prolonged clearance times were strongly related to the length of history (r = 0.90; P less than 0.01). The prolongation of half-clearance times correlated poorly with splenic size suggesting a functional impairment of the reticuloendothelial system.
first_indexed 2024-03-07T02:41:24Z
format Journal article
id oxford-uuid:aa9318fb-517f-4135-8199-c0a1d3d130a1
institution University of Oxford
language English
last_indexed 2024-03-07T02:41:24Z
publishDate 1981
publisher Informa Healthcare
record_format dspace
spelling oxford-uuid:aa9318fb-517f-4135-8199-c0a1d3d130a12022-03-27T03:16:04ZSplenic phagocytic function in patients with inflammatory bowel disease.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:aa9318fb-517f-4135-8199-c0a1d3d130a1EnglishSymplectic Elements at OxfordInforma Healthcare1981Jewell, DBerney, JPettit, JSplenic phagocytic function has been assessed in patients with inflammatory bowel disease. No Howell-Jolly bodies were found on blood film examination. Slow clearance times of heat damaged red cells were found in 13 of 16 patients with ulcerative colitis compared with 4 of 17 patients with Crohn's disease (P less than 0.01). For ulcerative colitis prolonged clearance times were strongly related to the length of history (r = 0.90; P less than 0.01). The prolongation of half-clearance times correlated poorly with splenic size suggesting a functional impairment of the reticuloendothelial system.
spellingShingle Jewell, D
Berney, J
Pettit, J
Splenic phagocytic function in patients with inflammatory bowel disease.
title Splenic phagocytic function in patients with inflammatory bowel disease.
title_full Splenic phagocytic function in patients with inflammatory bowel disease.
title_fullStr Splenic phagocytic function in patients with inflammatory bowel disease.
title_full_unstemmed Splenic phagocytic function in patients with inflammatory bowel disease.
title_short Splenic phagocytic function in patients with inflammatory bowel disease.
title_sort splenic phagocytic function in patients with inflammatory bowel disease
work_keys_str_mv AT jewelld splenicphagocyticfunctioninpatientswithinflammatoryboweldisease
AT berneyj splenicphagocyticfunctioninpatientswithinflammatoryboweldisease
AT pettitj splenicphagocyticfunctioninpatientswithinflammatoryboweldisease