Splenic phagocytic function in patients with inflammatory bowel disease.
Splenic phagocytic function has been assessed in patients with inflammatory bowel disease. No Howell-Jolly bodies were found on blood film examination. Slow clearance times of heat damaged red cells were found in 13 of 16 patients with ulcerative colitis compared with 4 of 17 patients with Crohn...
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Format: | Journal article |
Jezik: | English |
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Informa Healthcare
1981
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author | Jewell, D Berney, J Pettit, J |
author_facet | Jewell, D Berney, J Pettit, J |
author_sort | Jewell, D |
collection | OXFORD |
description | Splenic phagocytic function has been assessed in patients with inflammatory bowel disease. No Howell-Jolly bodies were found on blood film examination. Slow clearance times of heat damaged red cells were found in 13 of 16 patients with ulcerative colitis compared with 4 of 17 patients with Crohn's disease (P less than 0.01). For ulcerative colitis prolonged clearance times were strongly related to the length of history (r = 0.90; P less than 0.01). The prolongation of half-clearance times correlated poorly with splenic size suggesting a functional impairment of the reticuloendothelial system. |
first_indexed | 2024-03-07T02:41:24Z |
format | Journal article |
id | oxford-uuid:aa9318fb-517f-4135-8199-c0a1d3d130a1 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T02:41:24Z |
publishDate | 1981 |
publisher | Informa Healthcare |
record_format | dspace |
spelling | oxford-uuid:aa9318fb-517f-4135-8199-c0a1d3d130a12022-03-27T03:16:04ZSplenic phagocytic function in patients with inflammatory bowel disease.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:aa9318fb-517f-4135-8199-c0a1d3d130a1EnglishSymplectic Elements at OxfordInforma Healthcare1981Jewell, DBerney, JPettit, JSplenic phagocytic function has been assessed in patients with inflammatory bowel disease. No Howell-Jolly bodies were found on blood film examination. Slow clearance times of heat damaged red cells were found in 13 of 16 patients with ulcerative colitis compared with 4 of 17 patients with Crohn's disease (P less than 0.01). For ulcerative colitis prolonged clearance times were strongly related to the length of history (r = 0.90; P less than 0.01). The prolongation of half-clearance times correlated poorly with splenic size suggesting a functional impairment of the reticuloendothelial system. |
spellingShingle | Jewell, D Berney, J Pettit, J Splenic phagocytic function in patients with inflammatory bowel disease. |
title | Splenic phagocytic function in patients with inflammatory bowel disease. |
title_full | Splenic phagocytic function in patients with inflammatory bowel disease. |
title_fullStr | Splenic phagocytic function in patients with inflammatory bowel disease. |
title_full_unstemmed | Splenic phagocytic function in patients with inflammatory bowel disease. |
title_short | Splenic phagocytic function in patients with inflammatory bowel disease. |
title_sort | splenic phagocytic function in patients with inflammatory bowel disease |
work_keys_str_mv | AT jewelld splenicphagocyticfunctioninpatientswithinflammatoryboweldisease AT berneyj splenicphagocyticfunctioninpatientswithinflammatoryboweldisease AT pettitj splenicphagocyticfunctioninpatientswithinflammatoryboweldisease |