A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.

A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.

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AIMS/HYPOTHESIS: In this study we aimed to replicate the previously reported association between the glycaemic response to metformin and the SNP rs11212617 at a locus that includes the ataxia telangiectasia mutated (ATM) gene in multiple additional populations. METHODS: Incident users of metformin s...

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Những tác giả chính: van Leeuwen, N, Nijpels, G, Becker, M, Deshmukh, H, Zhou, K, Stricker, B, Uitterlinden, A, Hofman, A, van 't Riet, E, Palmer, C, Guigas, B, Slagboom, P, Durrington, P, Calle, R, Neil, A, Hitman, G, Livingstone, S, Colhoun, H, Holman, R, McCarthy, M, Dekker, J, 't Hart, L, Pearson, E
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2012

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