Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel.
ATP-sensitive potassium channels (K(ATP)) are formed from four pore-forming Kir6.2 subunits complexed with four regulatory sulfonylurea receptor subunits (SUR1 in pancreatic beta-cells, SUR2A in heart). The sensitivity of the channel to different sulfonylureas depends on the SUR isoform. In particul...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
1999
|
Search Result 1
Identification of the high affinity tolbutamide site on the SUR1 subunit of the K-ATP channel
Published 1999
Journal article