Enantioselective synthesis of 4- and 6-azaindolines by a cation-directed cyclization
Functionalized 4- and 6-azaindolines are accessible with high levels of enantioselectivity by the cation-directed cyclization of aminopyridine-derived imines via phase-transfer catalysis. The extension of this methodology to diastereoselective cyclizations is also described.
| Príomhchruthaitheoirí: | , , , , |
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| Formáid: | Journal article |
| Foilsithe / Cruthaithe: |
American Chemical Society
2016
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| Achoimre: | Functionalized 4- and 6-azaindolines are accessible with high levels of enantioselectivity by the cation-directed cyclization of aminopyridine-derived imines via phase-transfer catalysis. The extension of this methodology to diastereoselective cyclizations is also described. |
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