DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes.
Quick and clean: A method for Pd-catalyzed Suzuki-Miyaura cross-coupling to iododeoxyuridine (IdU) in DNA is described. Key to the reactivity is the choice of the ligand and the buffer. A covalent [Pd]-DNA intermediate was isolated and characterized. Photocrosslinking probes were generated to trap p...
| Hoofdauteurs: | , , , , |
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| Formaat: | Journal article |
| Taal: | English |
| Gepubliceerd in: |
2013
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| _version_ | 1826290334536040448 |
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| author | Lercher, L McGouran, J Kessler, B Schofield, C Davis, B |
| author_facet | Lercher, L McGouran, J Kessler, B Schofield, C Davis, B |
| author_sort | Lercher, L |
| collection | OXFORD |
| description | Quick and clean: A method for Pd-catalyzed Suzuki-Miyaura cross-coupling to iododeoxyuridine (IdU) in DNA is described. Key to the reactivity is the choice of the ligand and the buffer. A covalent [Pd]-DNA intermediate was isolated and characterized. Photocrosslinking probes were generated to trap proteins that bind to epigenetic DNA modifications. |
| first_indexed | 2024-03-07T02:42:36Z |
| format | Journal article |
| id | oxford-uuid:aaf45d95-ea81-40c5-a6d0-b4809c55ea6d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:42:36Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:aaf45d95-ea81-40c5-a6d0-b4809c55ea6d2022-03-27T03:18:44ZDNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:aaf45d95-ea81-40c5-a6d0-b4809c55ea6dEnglishSymplectic Elements at Oxford2013Lercher, LMcGouran, JKessler, BSchofield, CDavis, BQuick and clean: A method for Pd-catalyzed Suzuki-Miyaura cross-coupling to iododeoxyuridine (IdU) in DNA is described. Key to the reactivity is the choice of the ligand and the buffer. A covalent [Pd]-DNA intermediate was isolated and characterized. Photocrosslinking probes were generated to trap proteins that bind to epigenetic DNA modifications. |
| spellingShingle | Lercher, L McGouran, J Kessler, B Schofield, C Davis, B DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes. |
| title | DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes. |
| title_full | DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes. |
| title_fullStr | DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes. |
| title_full_unstemmed | DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes. |
| title_short | DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes. |
| title_sort | dna modification under mild conditions by suzuki miyaura cross coupling for the generation of functional probes |
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