DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes.

DNA modification under mild conditions by Suzuki-Miyaura cross-coupling for the generation of functional probes.

Quick and clean: A method for Pd-catalyzed Suzuki-Miyaura cross-coupling to iododeoxyuridine (IdU) in DNA is described. Key to the reactivity is the choice of the ligand and the buffer. A covalent [Pd]-DNA intermediate was isolated and characterized. Photocrosslinking probes were generated to trap p...

书目详细资料
Main Authors:	Lercher, L, McGouran, J, Kessler, B, Schofield, C, Davis, B
格式:	Journal article
语言:	English
出版:	2013

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