Structurally encoded intraclass differences in EphA clusters drive distinct cell responses.

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses.

他のバージョン（1件）を表示する

Functional outcomes of ephrin binding to Eph receptors (Ephs) range from cell repulsion to adhesion. Here we used cell collapse and stripe assays, showing contrasting effects of human ephrinA5 binding to EphA2 and EphA4. Despite equivalent ligand binding affinities, EphA4 triggered greater cell coll...

書誌詳細
主要な著者:	Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A, Klein, R, Jones, E
フォーマット:	Journal article
言語:	English
出版事項:	2013

類似資料

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses
著者:: Seiradake, E, 等
出版事項: (2013)

Structures of the EphA2 receptor at the membrane: Role of lipid interactions
著者:: Chavent, M, 等
出版事項: (2017)

An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly.
著者:: Seiradake, E, 等
出版事項: (2010)

Ephrin Receptors (Eph): EphA1, EphA5, and EphA7 Expression in Uveal Melanoma—Associations with Clinical Parameters and Patient Survival
著者:: Malgorzata Gajdzis, 等
出版事項: (2020-09-01)

Interactions of the EphA2 kinase domain with PIPs in membranes: implications for receptor function
著者:: Chavent, M, 等
出版事項: (2018)

Targeting EphA2 in cancer
著者:: Ta Xiao, 等
出版事項: (2020-08-01)

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia.
著者:: Sara Charmsaz, 等
出版事項: (2015-01-01)

Development of an In-House EphA2 ELISA for Human Serum and Measurement of Circulating Levels of EphA2 in Hypertensive Patients with Renal Dysfunction
著者:: Maki Murakoshi, 等
出版事項: (2022-12-01)

Patterned Substrate of Mobile and Immobile Ligands to Probe EphA2 Receptor Clustering
著者:: Zhongwen Chen, 等
出版事項: (2022-06-01)

Author Correction: The EphA2 receptor is activated through induction of distinct, ligand-dependent oligomeric structures
著者:: Deo R. Singh, 等
出版事項: (2018-04-01)

Preclinical and Toxicology Assessment of ALW-II-41-27, an Inhibitor of the Eph Receptor A2 (EphA2)
著者:: Theodore J. Kottom, 等
出版事項: (2024-08-01)

EphA7 isoforms differentially regulate cortical dendrite development.
著者:: Carrie E Leonard, 等
出版事項: (2020-01-01)

Upregulation of EphA Receptor Expression in the Injured Adult Rat Spinal Cord
著者:: Christopher A. Willson, 等
出版事項: (2002-04-01)

Role of EphA4 and EphrinB3 in local neuronal circuits that control walking.
著者:: Kullander, K, 等
出版事項: (2003)

Effects of Eph/ephrin signalling and human Alzheimer's disease-associated EphA1 on Drosophila behaviour and neurophysiology
著者:: Edgar Buhl, 等
出版事項: (2022-08-01)

Targeting the EphA2 pathway: could it be the way for bone sarcomas?
著者:: Giorgia Giordano, 等
出版事項: (2024-09-01)

EphA‐Mediated Regulation of Stomatin Expression in Prostate Cancer Cells
著者:: Masanari Nishida, 等
出版事項: (2024-10-01)

Theoretical Model of EphA2-Ephrin A1 Inhibition
著者:: Wiktoria Jedwabny, 等
出版事項: (2018-07-01)

Inhibition of VEGF-Dependent Multistage Carcinogenesis by Soluble EphA Receptors
著者:: Nikki Cheng, 等
出版事項: (2003-09-01)

Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma
著者:: Zhongzhen Yi, 等
出版事項: (2018-06-01)

Anti-EphA2 Antibodies Decrease EphA2 Protein Levels in Murine CT26 Colorectal and Human MDA-231 Breast Tumors But Do Not Inhibit Tumor Growth
著者:: David Kiewlich, 等
出版事項: (2006-01-01)

COMPLEMENTARY EXPRESSION OF EphA7 AND SCO-SPONDIN DURING POSTERIOR COMMISSURE DEVELOPMENT
著者:: Karen eStanic, 等
出版事項: (2014-06-01)

Drug-resistant cancer cell-derived exosomal EphA2 promotes breast cancer metastasis via the EphA2-Ephrin A1 reverse signaling
著者:: Zicong Gao, 等
出版事項: (2021-04-01)

EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria.
著者:: Thayer K Darling, 等
出版事項: (2020-01-01)

Probing the effect of clustering on EphA2 receptor signaling efficiency by subcellular control of ligand-receptor mobility
著者:: Zhongwen Chen, 等
出版事項: (2021-08-01)

EphA4 defines a class of excitatory locomotor-related interneurons.
著者:: Butt, S, 等
出版事項: (2005)

Unveiling the therapeutic promise of EphA2 in glioblastoma: a comprehensive review
著者:: Caohang Qiu, 等
出版事項: (2024-09-01)

EphA3 CAR T cells are effective against glioblastoma in preclinical models
著者:: Xiang Li, 等
出版事項: (2024-08-01)

#50. Investigating the role of EphA2 in breast cancer bone metastasis
著者:: Verra Ngwa, 等
出版事項: (2024-04-01)

Effective Tumor Targeting by EphA2-Agonist-Biotin-Streptavidin Conjugates
著者:: Parima Udompholkul, 等
出版事項: (2021-06-01)

EphA7 promotes myogenic differentiation via cell-cell contact
著者:: Laura L Arnold, 等
出版事項: (2020-04-01)

Role of EphA2 in host defense against oro-pharyngeal candidiasis
著者:: Ingar Olsen
出版事項: (2020-01-01)

Engineering of monobody conjugates for human EphA2-specific optical imaging.
著者:: Min-A Kim, 等
出版事項: (2017-01-01)

Peripheral loss of EphA4 ameliorates TBI-induced neuroinflammation and tissue damage
著者:: Elizabeth A. Kowalski, 等
出版事項: (2019-11-01)

EphA5 Silencing Increases the Radiosensitivity of ESCC Cells Through ATM-Dependent Pathway
著者:: Zhang R, 等
出版事項: (2020-10-01)

Therapeutic Targeting of Pancreatic Cancer via EphA2 Dimeric Agonistic Agents
著者:: Ahmed F. Salem, 等
出版事項: (2020-05-01)

EphA2 is a functional entry receptor for HCMV infection of glioblastoma cells.
著者:: Xiao-Dong Dong, 等
出版事項: (2023-05-01)

Overexpression of hepatocyte EphA2 enhances liver-stage infection by Plasmodium vivax
著者:: Sittinont Chainarin, 等
出版事項: (2022-12-01)

Modeling development in retinal afferents: retinotopy, segregation, and ephrinA/EphA mutants.
著者:: Keith B Godfrey, 等
出版事項: (2014-01-01)

The identification and validation of EphA7 hypermethylation, a novel biomarker, in cervical cancer
著者:: Wenfan Zhang, 等
出版事項: (2022-06-01)