Structurally encoded intraclass differences in EphA clusters drive distinct cell responses.

Functional outcomes of ephrin binding to Eph receptors (Ephs) range from cell repulsion to adhesion. Here we used cell collapse and stripe assays, showing contrasting effects of human ephrinA5 binding to EphA2 and EphA4. Despite equivalent ligand binding affinities, EphA4 triggered greater cell coll...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A, Klein, R, Jones, E
Format:	Journal article
Język:	English
Wydane:	2013

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses od Seiradake, E, Schaupp, A, Del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A, Klein, R, Jones, E

Wydane 2013

Journal article

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses.

Structurally encoded intraclass differences in EphA clusters drive distinct cell responses od Seiradake, E, Schaupp, A, Del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A, Klein, R, Jones, E

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