Role of CD8 in aberrant function of cytotoxic T lymphocytes.

Role of CD8 in aberrant function of cytotoxic T lymphocytes.

Using H-2Kd-restricted photoprobe-specific cytotoxic T lymphocyte (CTL) clones, which permit assessment of T cell receptor (TCR)-ligand interactions by TCR photoaffinity labeling, we observed that the efficiency of antigen recognition by CTL was critically dependent on the half-life of TCR-ligand co...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Kessler, B, Hudrisier, D, Cerottini, J, Luescher, I
Natura:	Journal article
Lingua:	English
Pubblicazione:	1997

Documenti analoghi

Peptide modification or blocking of CD8, resulting in weak TCR signaling, can activate CTL for Fas- but not perforin-dependent cytotoxicity or cytokine production.
di: Kessler, B, et al.
Pubblicazione: (1998)

The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement.
di: Hudrisier, D, et al.
Pubblicazione: (1998)

The efficiency of antigen recognition by CTL is determined by the frequency of serial TCR engagement.
di: Hudrisier, D, et al.
Pubblicazione: (1998)

Effects of epitope modification on T cell receptor-ligand binding and antigen recognition by seven H-2Kd-restricted cytotoxic T lymphocyte clones specific for a photoreactive peptide derivative.
di: Kessler, B, et al.
Pubblicazione: (1997)

Antagonism of cytotoxic T-lymphocyte activation by soluble CD8.
di: Sewell, A, et al.
Pubblicazione: (1999)

Evaluation of the Role of Tumor-Infiltrating Lymphocytes and CD8+ Cytotoxic Lymphocytes in the Survival of Patients with Breast Cancer
di: Shahram Shojaei, et al.
Pubblicazione: (2023-01-01)

Presence of lymphocytic infiltrate cytotoxic T lymphocyte CD3+, CD8+, and immunoscore as prognostic marker in patients after radical cystectomy.
di: Alice Yu, et al.
Pubblicazione: (2018-01-01)

Anaplasma phagocytophilum-Related Defects in CD8, NKT, and NK Lymphocyte Cytotoxicity
di: Diana G. Scorpio, et al.
Pubblicazione: (2018-04-01)

THE ROLE OF SUBPOPULATIONS OF CD8+ T LYMPHOCYTES IN THE DEVELOPMENT OF PREGNANCY
di: O. I. Stepanova, et al.
Pubblicazione: (2018-11-01)

Extracellular CIRP induces CD4CD8αα intraepithelial lymphocyte cytotoxicity in sepsis
di: Yuichi Akama, et al.
Pubblicazione: (2024-02-01)

Rhesus Cytomegalovirus-Specific CD8+ Cytotoxic T Lymphocytes Do Not Become Functionally Exhausted in Chronic SIVmac239 Infection
di: Brandon C. Rosen, et al.
Pubblicazione: (2020-08-01)

Immune recognition of HLA molecules downmodulates CD8 expression on cytotoxic T lymphocytes.
di: Robbins, P, et al.
Pubblicazione: (1991)

CD8+ T Lymphocyte and NK Cell Network: Circuitry in the Cytotoxic Domain of Immunity
di: Roman V. Uzhachenko, et al.
Pubblicazione: (2019-08-01)

CYTOTOXIC ACTIVITY OF DENDRITIC CELLS AGAINST ACTIVATED CD4+ AND CD8+T-LYMPHOCYTES IN THE CULTURE IN VITRO
di: T. V. Tyrinova, et al.
Pubblicazione: (2012-05-01)

Discriminated selection among viral peptides with the appropriate anchor residues: implications for the size of the cytotoxic T-lymphocyte repertoire and control of viral infection.
di: Oldstone, M, et al.
Pubblicazione: (1995)

Selective miRNA inhibition in CD8+ cytotoxic T lymphocytes enhances HIV-1 specific cytotoxic responses
di: Nadia Madrid-Elena, et al.
Pubblicazione: (2022-09-01)

CD8 independence and specificity of cytotoxic T lymphocytes restricted by HLA-Aw68.1.
di: Cerundolo, V, et al.
Pubblicazione: (1991)

Generation and purification of CD8+ melan-A-specific cytotoxic T lymphocytes for adoptive transfer in tumor immunotherapy.
di: Oelke, M, et al.
Pubblicazione: (2000)

Functional characterization of CD8(+) antigen-specific cytotoxic T lymphocytes after enrichment based on cytokine secretion: comparison with the MHC-tetramer technology.
di: Oelke, M, et al.
Pubblicazione: (2000)

Therapeutic implications of variable expression of CD52 on clonal cytotoxic T cells in CD8+ large granular lymphocyte leukemia
di: Sanjay R. Mohan, et al.
Pubblicazione: (2009-10-01)

Control of mucosal virus infection by influenza nucleoprotein-specific CD8<sup>+ </sup>cytotoxic T lymphocytes
di: Couch Robert B, et al.
Pubblicazione: (2007-06-01)

CD8<sup>+</sup>, HLA-unrestricted, cytotoxic T-lymphocyte line against malignant melanoma
di: Guerry DuPont, et al.
Pubblicazione: (2005-11-01)

The Relationship of CD8-Positive Cytotoxic T Lymphocytes and other Clinicopathologic Features with Survival in Breast Cancer
di: Simin Hemati, et al.
Pubblicazione: (2017-11-01)

NFAT2 regulates generation of innate-like CD8+ T lymphocytes and CD8+ T lymphocytes responses
di: Emilia Pachulec, et al.
Pubblicazione: (2016-10-01)

Roles of CD3, CD4 and CD8 in synovial lymphocytes of rheumatoid arthritis
di: Guangyi Xiong, et al.
Pubblicazione: (2022-06-01)

The potential role of CD8+ cytotoxic T lymphocytes and one branch connected with tissue-resident memory in non-luminal breast cancer
di: Ziqi Zhao, et al.
Pubblicazione: (2024-07-01)

Aberrant CD3-Positive, CD8-Low, CD7-Negative Lymphocytes May Appear During Viral Infections and Mimic Peripheral T-Cell Lymphoma
di: Andreas Klameth, et al.
Pubblicazione: (2020-04-01)

Description of HLA class I- and CD8-deficient patients: Insights into the function of cytotoxic T lymphocytes and NK cells in host defense.
di: Cerundolo, V, et al.
Pubblicazione: (2006)

Cytotoxic function of CD8+ T lymphocytes isolated from patients with acute severe cerebral infarction: an assessment of stroke-induced immunosuppression
di: Li Gang, et al.
Pubblicazione: (2013-01-01)

Differential Requirement of Cd8 Enhancers E8I and E8VI in Cytotoxic Lineage T Cells and in Intestinal Intraepithelial Lymphocytes
di: Alexandra Franziska Gülich, et al.
Pubblicazione: (2019-03-01)

CD8beta endows CD8 with efficient coreceptor function by coupling T cell receptor/CD3 to raft-associated CD8/p56(lck) complexes.
di: Arcaro, A, et al.
Pubblicazione: (2001)

TYK2 signaling promotes the development of autoreactive CD8+ cytotoxic T lymphocytes and type 1 diabetes
di: Keiichiro Mine, et al.
Pubblicazione: (2024-02-01)

Global activation of CD8+ cytotoxic T lymphocytes correlates with an impairment in regulatory T cells in patients with generalized vitiligo.
di: Yang Lili, et al.
Pubblicazione: (2012-01-01)

Intratumoral CD8⁺ cytotoxic lymphocyte is a favorable prognostic marker in node-negative breast cancer.
di: Zonglin Chen, et al.
Pubblicazione: (2014-01-01)

Generation of Primary Peptide-Specific Cd8 Cytotoxic T-lymphocytes in Vitro using allogeneic dendritic cells
di: Madhusudan V. Peshwa, et al.
Pubblicazione: (1998-01-01)

Intrinsic PD‐L1 promotes antitumor activity of CD8+ cytotoxic T lymphocytes via in cis interaction with CD80
di: Yuming Ding, et al.
Pubblicazione: (2022-08-01)

Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response.
di: Jones, N, et al.
Pubblicazione: (2004)

CD40 ligand-mediated interactions are involved in the generation of memory CD8(+) cytotoxic T lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infection.
di: Borrow, P, et al.
Pubblicazione: (1998)

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation.
di: Read, S, et al.
Pubblicazione: (2000)

Comparison of CD4+ and CD8+ T- lymphocyte in Helicobacter pylori-negative functional dyspepsia
di: Leila Vahedi, et al.
Pubblicazione: (2020-03-01)