Hepatocyte growth factor can substitute for M-CSF to support osteoclastogenesis.
Osteopetrotic mice lacking functional macrophage-colony stimulating factor (M-CSF) recover with ageing, suggesting that alternative osteoclastogenesis pathways exist. Hepatocyte growth factor (HGF) and M-CSF signal through tyrosine kinase receptors and phosphorylate common transducers and effectors...
Main Authors: | Adamopoulos, I, Xia, Z, Lau, Y, Athanasou, N |
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格式: | Journal article |
语言: | English |
出版: |
2006
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