When is a hydrophobic gate not a hydrophobic gate?
<p>The flux of ions through a channel is most commonly regulated by changes that result in steric occlusion of its pore. However, ion permeation can also be prevented by formation of a desolvation barrier created by hydrophobic residues that line the pore. As a result of relatively minor struc...
Main Authors: | Seiferth, D, Biggin, PC, Tucker, SJ |
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Format: | Journal article |
Language: | English |
Published: |
Rockefeller University Press
2022
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