When is a hydrophobic gate not a hydrophobic gate?

When is a hydrophobic gate not a hydrophobic gate?

<p>The flux of ions through a channel is most commonly regulated by changes that result in steric occlusion of its pore. However, ion permeation can also be prevented by formation of a desolvation barrier created by hydrophobic residues that line the pore. As a result of relatively minor struc...

Descripció completa

Dades bibliogràfiques
Autors principals:	Seiferth, D, Biggin, PC, Tucker, SJ
Format:	Journal article
Idioma:	English
Publicat:	Rockefeller University Press 2022

Ítems similars

A hydrophobic gating mechanism for nanopores
per: Beckstein, O, et al.
Publicat: (2001)

Hydrophobic gating in ion channels.
per: Aryal, P, et al.
Publicat: (2015)

Water and hydrophobic gates in ion channels and nanopores
per: Rao, S, et al.
Publicat: (2018)

Molecular simulations of hydrophobic gating of pentameric ligand gated ion channels: Insights into water and ions
per: Rao, S, et al.
Publicat: (2021)

Hydrophobic gating in BK channels
per: Zhiguang Jia, et al.
Publicat: (2018-08-01)

Hydrophobic gating and functional annotation of ion channels
per: Klesse, G
Publicat: (2019)

Hydrophobically gated memristive nanopores for neuromorphic applications
per: Gonçalo Paulo, et al.
Publicat: (2023-12-01)

Publisher Correction: Hydrophobic gating in BK channels
per: Zhiguang Jia, et al.
Publicat: (2020-09-01)

A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates
per: Rao, S, et al.
Publicat: (2019)

Hydrophobic Gating of Ion Permeation in Magnesium Channel CorA.
per: Chris Neale, et al.
Publicat: (2015-07-01)

Electric field induced wetting of a hydrophobic gate in a model nanopore based on the 5-HT3 receptor channel
per: Klesse, G, et al.
Publicat: (2020)

Voltage gating of a biomimetic nanopore: Electrowetting of a hydrophobic barrier
per: Sansom, M, et al.
Publicat: (2017)

A hydrophobic gate in an ion channel: the closed state of the nicotinic acetylcholine receptor.
per: Beckstein, O, et al.
Publicat: (2006)

Contribution of the central hydrophobic residue in the PXP motif of voltage-dependent K+ channels to S6 flexibility and gating properties.
per: Imbrici, P, et al.
Publicat: (2009)

Hydrophobic gating in bundle-crossing ion channels: a case study of TRPV4
per: Jian Huang, et al.
Publicat: (2023-10-01)

The importance of surface character, geometry and flexibility in a hydrophobic gating mechanism for ion channels
per: Beckstein, O, et al.
Publicat: (2004)

Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts
per: Seiferth, D, et al.
Publicat: (2023)

Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment
per: Bharambe, Nikhil, et al.
Publicat: (2024)

Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment
per: Nikhil Bharambe, et al.
Publicat: (2024-04-01)

Voltage controlled iontronic switches: a computational method to predict electrowetting in hydrophobically gated nanopores
per: Gonçalo Paulo, et al.
Publicat: (2024-01-01)

A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels
per: Wang Zheng, et al.
Publicat: (2019-01-01)

The structure of a potassium-selective ion channel reveals a hydrophobic gate regulating ion permeation
per: Patricia S. Langan, et al.
Publicat: (2020-09-01)

STIM1 activates CRAC channels through rotation of the pore helix to open a hydrophobic gate
per: Megumi Yamashita, et al.
Publicat: (2017-02-01)

Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels
per: Wang Zheng, et al.
Publicat: (2018-06-01)

Hydroxide and Hydrophobic Tetrabutylammonium Ions at the Hydrophobe–Water Interface
per: Alex M. Djerdjev, et al.
Publicat: (2025-02-01)

State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane
per: Dämgen, MA, et al.
Publicat: (2021)

Channel gating: twist to open.
per: Biggin, P, et al.
Publicat: (2001)

Author Correction: Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels
per: Wang Zheng, et al.
Publicat: (2019-03-01)

Computational investigation of voltage-gated sodium channel β3 subunit dynamics
per: Glass, WG, et al.
Publicat: (2020)

The Influence of Hydrophobic Structure on the Performance of Pt/Ceramic Hydrophobic Catalyst
per: JIA Qingqing;HU Shilin;LIU Yaming
Publicat: (2021-02-01)

Simulation approaches to ion channel gating
per: Biggin, P, et al.
Publicat: (2002)

Adsorption of Hydrophobically Modified Polyelectrolytes on Hydrophobic Substrates Adsorption de polyélectrolytes modifiés hydrophobiquement sur les substrats hydrophobes
per: Mays J. W., et al.
Publicat: (2006-12-01)

Molecular simulation of the Kv7.4[ΔS269] mutant channel reveals that ion conduction in the cavity is perturbed due to hydrophobic gating
per: Md Harunur Rashid
Publicat: (2021-03-01)

Anti-Fouling Performance of Hydrophobic Hydrogels with Unique Surface Hydrophobicity and Nanoarchitectonics
per: Liangpeng Zeng, et al.
Publicat: (2022-06-01)

Tight hydrophobic core and flexible helices yield MscL with a high tension gating threshold and a membrane area mechanical strain buffer
per: Arjun Sharma, et al.
Publicat: (2023-05-01)

The Hydrophobization of Active Carbons
per: N.S. Polyakov, et al.
Publicat: (1993-03-01)

Hydrophobic Waters in Bromodomains
per: Serena G. Piticchio, et al.
Publicat: (2019-08-01)

Hydrophobized clay gypsum
per: Asamatdinov Marat, et al.
Publicat: (2023-01-01)

Hydrophobic interactions in proteins
per: Louis, C
Publicat: (1968)

Piper's gate /
per: 326027 Manley-Tucker, Audrie
Publicat: ([s d)